A study suggests melatonin may provide mild relief for chronic muscle and joint pain, though its effects are limited.Researchers analyzed 23 clinical trials involving over 2,000 participants, finding that melatonin reduced pain scores by about nine points on a 100-point scale.

However, the benefits are modest compared to anti-inflammatory drugs, and the drug's effectiveness may depend on pre-existing sleep issues or health conditions.The study also found limited impact on post-surgical pain, with only a 2.5-point improvement.While melatonin is generally safe for short-term use, side effects like dizziness and nausea may occur.Regulatory differences exist globally, with the U.S.classifying it as a supplement and the UK requiring a prescription.

The findings indicate melatonin could complement existing treatments like physiotherapy and anti-inflammatory medications but should not replace them.Further research is needed to determine optimal dosages and target populations.