A two-year structured lifestyle program significantly improved cognitive function in older adults, according to the LatAm-FINGERS trial published in The Lancet.

The study involved 1,065 participants aged 60-77 across 11 Latin American countries, making it the first large-scale brain health trial tailored to the region.

Participants engaged in supervised exercise four days a week, followed a brain-healthy MIND diet adapted to local cultures, and completed computer-based cognitive training sessions.They also received regular health monitoring and social engagement activities.

Compared to a control group receiving general health advice, the intervention group showed 55% greater annual improvements in memory and processing speed, with benefits consistent across age, education, ethnicity, and genetic risk factors.

The trial highlights culturally adapted lifestyle changes as an effective strategy for cognitive preservation in aging populations, though longer follow-up is needed to confirm dementia prevention effects.